Clinical manifestations of coinfection between covid-19 and dengue in adults: integrative review

Abstract

Objective: to identify the evidence available in the scientific literature on the clinical manifestations of co-infection between Covid-19 and Dengue in adults. Method: integrative review, carried out in the MEDLINE/PUBMED, LILACS, IBECS, WoS and EMBASE databases, in June 2021. The descriptors "adult", "Coronavirus infections" and "dengue" with their synonyms were crossed by means of operators Booleans AND and OR. Results: 23 studies were included, with a predominance of 19 case studies (82.6%). The main clinical manifestations identified from the studies were: fever, headache, dyspnea, cough, myalgia, retro orbital pain, and skin rash. In addition to laboratory findings such as: thrombocytopenia, lymphopenia, and leukopenia. Conclusion: covid-19 and Dengue coinfection was identified and the need for an immediate search for a differential diagnosis is pointed out, in order to prevent clinical problems and reduce unexpected outcomes.